PHÂN LẬP HỢP CHẤT FUB-AMB TRONG GIÁM ĐỊNH PHÁP Y CÁC MẪU CẦN SA TỔNG HỢP THU TẠI VIỆT NAM TỪ 2016 - 2018

Abstract

Backgrounds: Synthetic cannabinoids are currently the largest group of new psychoactive substances and one of the most recent synthetic cannabinoids that have appeared in Vietnam is FUB-AMB. In this study, the first FUB-AMB compound in Vietnam was isolated and structure determined by spectroscopic analytical methods (UV, IR, ¹H-NMR, ¹³C-NMR). Subjects and methods:: Isolation and purity of FUB-AMB compounds used as working standard (substance). The samples of synthetic cannabinoids were collected from cases in Vietnam from 2016 to 2018, and then watered with methanol at 40°C, recovered solvent to get total methanol extract. Isolation of fractions from methanol extract by column chromatography to collect FUB-AMB. Results: FUB-AMB was collected from 10 g of total metanol extract with the purity were 98,34%. Conclusions: By chromatography methods, the compound FUB-AMB (1g) was isolated. From this result, FUB-AMB can be used as a standard substance in testing, contributing to the development of a method for analyzing narcotic drugs in the synthetic cannabinoids to support the drug  crimes handling of the authorities.