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Date Published: 17/07/2022
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DOI: https://doi.org/10.51298/vmj.v516i1.2946
Issue
Vol. 516 No. 1 (2022)
Section
Các bài báo
How to Cite
Quang Hưng, N. ., Đức Bình, V. ., Quang Tường, L. ., Quang Chiêm, L. ., Thị Hồng Nhung, T. ., & Hà Thanh, N. . (2022). PROGNOSTIC FACTORS OF MARGINAL ZONE B-CELL LYMPHOMA. Vietnam Medical Journal, 516(1). https://doi.org/10.51298/vmj.v516i1.2946

PROGNOSTIC FACTORS OF MARGINAL ZONE B-CELL LYMPHOMA

Nguyễn Quang Hưng1,, Vũ Đức Bình1, Lê Quang Tường1, Lê Quang Chiêm1, Trần Thị Hồng Nhung1, Nguyễn Hà Thanh1,2
1 National Institute of Hematology and Blood Transfusion
2 Hanoi Medical University

Main Article Content

Abstract

A cross-sectional descriptive study was conducted to analyze some prognostic factors of marginal zone B-cell lymphoma at the National Institute of Hematology and Blood Transfusion. The study population included 86 patients with newly diagnosed marginal zone B-cell lymphoma (MZL). The study results showed that the likelihood of patients at stage III-IV was higher when they were 60 years old, had syndrome B, hemoglobin concentration decreases <120 g/l, platelet count <150 G/L, abnormal white blood cell count (>10 or <4 G/L), increased lymphocyte count >3G/L, bone marrow biopsy results with marrow invasion, LDH increased >460U/l, B2M increased >2.2U/l, Ki67 index increased >30%. The likelihood of patients with marrow invasion was higher when hemoglobin levels decreased<120 g/l, platelet counts decreased<150 G/L, lymphocyte counts increased>3G/L, LDH increased>460U /l, B2M increased >2.2U/l, Ki67 index increased >30%. There was a correlation between the prognostic indicators of the disease: hemoglobin levels, LDH, B2M and Ki67.

Article Details

Keywords

prognosis, B-cell marginal zone lymphoma

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