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HEMOGLOBINOPATHIES AND HERMOLOGICAL CHARACTERISTICS OF THE FRESH MAN STUDENTS IN CAN THO UNIVERSITY OF MEDICINE AND PHARMACY WITH MICROCYTIC HYPOCHROMIC ANEMIA
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Abstract
Background: Every year, students of Can Tho University of Medicine and Pharmacy (University of Medicine and Pharmacy) have a health check before admission and there are a large number of students (students) with hypochromic small red blood cells, a group of subjects at risk. Very high risk of carrying the hemoglobin disease gene. Objectives: To identify hemoglobin (Hb) disease forms and hematological characteristics of Hb disease forms in first-year students of the University of Traditional Chinese Medicine with hypochromic small red blood cells. Subjects and methods: A cross-sectional descriptive study on 219 hypochromic microcytic erythrocytes. Results: 39.7% of students had abnormalities in MCH (<27pg) and 63.3% of students had abnormalities in both MCV (<80fL) and MCH; There are 3 types of Hb disease, accounting for 32.9% total (72/219), heterozygous HbE (HbAE) accounted for 24.7%; Heterozygous β-Thalasemia (β-Thal) form accounted for 7.3% and HbH form of α-Thal disease (HbH) accounted for 0.9%. There are 58/72 (80.5%) Kinh people and 39/72 (54.2%) students are female; residence in Can Tho (15.3%) and other localities (84.7%). On hematological characteristics: red blood cell count; MCV; MCH, the average Hb index of β-Thal disease is: 6.06 ± 0.57x1012/L, respectively; 70.43 ± 5.37fL; 21.09 ± 2.06pg; 12.81 ± 0.83g/dL; of HbAE disease are: 5.59± 0.55x1012/L, respectively; 79.44 ± 3.42fL; 25.2 ± 1.48pg; 14.19 ± 0.52 g/dL and HbH form is: 7 ± 0.0x1012/L; 66 ± 0.85fL; 16.65±0.07pg; 11 ± 0.0g/dL. Conclusions: The total prevalence of Hb among first-year students of the University of Traditional Chinese Medicine is 32.9%. There are 3 types of disease identified as: heterozygous HbE 24.7%; Heterozygous β-Thalaseemia was 7.3% and HbH form of α-Thal disease was lowest, 0.9%. Red blood cell count values; MCV; MCH, mean Hb index differs according to Hb disease types.
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Keywords
hemoglobinopathies, microcytic hypochromic anemia, students, CTMP
References
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