NHẬN XÉT MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN CÓ CHỈ ĐỊNH THAY VAN ĐỘNG MẠCH CHỦ BẰNG VAN SINH HỌC KHÔNG GỌNG FREEDOM SOLO TẠI BỆNH VIỆN BẠCH MAI

Abstract

Objectives: To investigate preoperative clinical and laboratory characteristics of patients who underwent aortic valve replacement with the Freedom Solo – a stentless bioprosthesis valve. Subjects and methods: This prospective study was carried out on 53 patients who underwent aortic valve replacement with Freedom Solo valve at Bach Mai Hospital, Ha Noi from January 2016 to May 2022. Results: The mean age was 62.8 ± 6.1 years old, and 67.9% were men. The main clinical symptom was chest pain (60.4%), and syncope appeared in 9.4% of patients. Heart failure classification according to NYHA preoperatively, most of them belonged to the NYHA II group (73.6%) and NYHA III group (22.6%); The most common comorbidities were hypertension (39.6%), type II diabetes (5.7%) and previously cerebrovascular accident (3.8%). Laboratory tests: 17% of patients with mild to moderate anemia; 5.7% of patients had atrial fibrillation before surgery. Echocardiography showed that the lesion morphology was mainly severe stenosis and regurgitation (83%); severe left ventricular hypertrophy with an average left ventricular mass index of 167.8 ± 59.6 g/m2; the mean trans aortic valve pressure was high (49.6 ± 25.4 mmHg). 20.8% of the study patients had a moderate decrease in left ventricular ejection fraction before surgery (30% < LVEF < 50%). Conclusions: Patients with aortic valve disease who were undergoing Freedom Solo bioprosthetic valve replacement often presented to the hospital with symptoms and severe left ventricular hypertrophy.