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Date Published: 31/07/2022
Abstract Views: 259
Views PDF: 469
DOI: https://doi.org/10.51298/vmj.v516i2.3031
Issue
Vol. 516 No. 2 (2022)
Section
Các bài báo
How to Cite
Văn Tam, T. ., Hữu Việt, Đinh ., Thị Mỹ Hạnh, P. ., Trọng Hoàng Hiệp, N. ., Minh Ngọc, P. ., Văn Ái, H. ., Đức Minh, P. ., Ngọc Nhất, N. ., Thị Thu Hiền, L. ., & Thế Sơn, T. . (2022). SOME SEMINAL CHARACTERISTICS, KAROTYPE AND THE TREATMENT OPTIONS IN INFERTILE MEN WITH ISOLATED AND COMBINED AZFc MICRODELETIONS. Vietnam Medical Journal, 516(2). https://doi.org/10.51298/vmj.v516i2.3031

SOME SEMINAL CHARACTERISTICS, KAROTYPE AND THE TREATMENT OPTIONS IN INFERTILE MEN WITH ISOLATED AND COMBINED AZFc MICRODELETIONS

Trịnh Văn Tam1,, Đinh Hữu Việt1, Phạm Thị Mỹ Hạnh1, Nguyễn Trọng Hoàng Hiệp1, Phạm Minh Ngọc1, Hoàng Văn Ái2, Phạm Đức Minh2, Nguyễn Ngọc Nhất2, Lê Thị Thu Hiền1, Trịnh Thế Sơn2
1 Andrology and Fertility Hospital of Hanoi
2 Vietnam Military Medical University

Main Article Content

Abstract

Objectives: To investigate some seminal characteristics, karotype and the treatment options in infertile men with isolated and combined AZFc microdeletions. Material and method: A retrospective, cross-sectional study method in 144 Vietnamese  men with isolated and combined AZFc microdeletions in patients with oligospermia or azoospermia at Hanoi Hospital of Andrology and Infertility from December 2016 to June 2021. Result: Isolated AZFc microdeletions accounts for the majority (54.17%) of AZFc microdeletions. 24.31% of patients with AZF microdeletions were accompanied by chromosomal abnormalities. Deletion of AZFa with AZFc resulted in 100% azoospermia. 40.97% of patients with AZF microdeletions have not been performed assisted reproduction. Most deletion basis zones of AZFc resulted in severe oligospermia. Conclusion: The semen analysis of patients with isolated AZFc microdeletions was the best, deletion of AZFa with AZFc resulted in 100% azoospermia. 24.31% of patients with AZF microdeletions were accompanied by chromosomal abnormalities. 40.97% of patients with AZF microdeletions have not been performed assisted reproduction.

Article Details

Keywords

Azoospermia, karotype, AZF, oligospermia

References

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