THE SURVIVAL OUTCOME OF CHEMOTHERAPY OF TRIPLET REGIMEN CAP IN METASTATIC SALIVARY GLAND CARCINOMA

Đỗ Hùng Kiên1,, Nguyễn Văn Tài1
1 Vietnam National Cancer Hospital

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Abstract

Objective: Evaluating the survival outcome of chemotherapy of triplet regimen CAP in metastatic salivary gland carcinoma at National Cancer Hospital from 2015 to 2021. Patients and method: Retrospective analysis of 21 patients with metastatic salivary gland carcinoma were diagnosed and treated with chemotherapy of CAP regimen at National Cancer Hospital from 2015 to 2021. Results: The average age was 50.6±5.5, male/female ratio was 1.6/1. Mean recurrent time was 22+6.3 months. The pathology of adenoid cystic tumor was observed in 76%. Primary carcinoma, 42.9% patients had tumor of parotid gland origin and 33.3% submaxillary gland origin. Oligometastasis, accounted for 57.1% and lung metastasis was dominated with 76.2%, then mediastinal nodes and bone metastasis. Average free-progression survival was 7.3±2.1 months. 1-year and 2-year free-progression survival rates were 51.9% and 39.0%, respectively. Average overall survival was 17.5±3.1 months. 1-year and 2-year overall survival rates were 46.8% and 33.4%, respectively. Conclusion: Chemotherapy of triplet regimen CAP showed good survival outcome in patients with metastatic salivary gland carcinoma, average overall survival was 17.5±3.1 month

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References

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