THE CLINICAL AND PARACLINICAL CHARACTERISTICS OF PATIENTS WITH BENIGN MEDIASTINAL TERATOMAS WHO WERE OPERATED ON AT VIET DUC UNIVERSITY HOSPITAL IN THE PERIOD 2015 - 2021

Phạm Hữu Lư 1,, Ngô Văn Nam2
1 Cardiovascular and Thoracic Center, Vietnam-Germany Friendship Hospital
2 Thanh Hoa Oncology Hospital

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Abstract

Objectives: To describe the clinical and subclinical characteristics of patients with benign mediastinal teratomas who were operated on at Viet Duc University Hospital in the period 2015 - 2021. Methods: A retrospective, cross-sectional descriptive study with all cases diagnosed as benign mediastinal teratomas operated at Viet Duc Friendship Hospital from January 2015 to December 2021. Results: Includes 46 patients, 15 men and 31 women. Mean age 28.98 ± 12.51 (12 - 66). Among 40 symptomatic cases, chest pain was the most common symptom (80.43%), the mean duration of the disease was 4.5 ± 8.2months. Computed tomography has high diagnostic results (100%). All tumors were located in the anterior mediastinum with an average tumor size of 8.4 ± 3.8 cm (2.7 – 17.4). There were 4 cases (8.7%) with genital lesions accompanied by uterine fibroids and ovarian cysts. Alpha-FP and beta-HCG tests were both within normal limits. Conclusion: Patients with benign mediastinal teratoma can be found at any age, with no gender difference, no specific clinical symptoms, the most common is chest pain, mostly located in the anterior mediastinum, it can be detected on chest radiographs and computed tomography. In some cases, care is needed to differentiate from malignant germ cell tumors.

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References

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