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CLINICAL AND PARACLINICAL CHARACTERISTICS HOSPITAL ADMITTED COVID-19 PATIENTS
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Abstract
Objectives: Describe the clinical and subclinical characteristics and determine the rate of admission to intensive care, mechanical ventilation and death of COVID-19 patients admitted to hcmc hospital for rehabilitation-professional diseases. Subjects and methods: We conducted a cross sectional descriptive study on 104 COVID-19 patients. Results and conclusion: 42.3% was male. Mean age 61.7 ± 13.7. The common symptoms were fever (76.9%), shortness of breath (74%), fatigue (53.8%). Common comorbidities were hypertension (53.8%), diabetes (25.9%), gastritis (19.2%), ischemic heart disease (15.4%). Most of the patients in the study had tachycardia, increased respiratory rate, decreased SpO2, the death group compared with the recovered group had a higher median respiratory rate (32 vs 24 breaths/minute) and a lower SpO2 (78% vs. 91%), (p < 0.001). Urea, Creatinine, AST, D-Dimer, Ferritin, CRP were higher in the mortality group than in the recovered group (p<0.05). The median sodium concentration in the death group was lower than in the recovered group (p=0.008). Abnormal features on chest xray were usually interstitial, nodular reticular, alveolar opacities, and pulmonary consolidation. Most of them had on both lungs, mainly focusing on the outer third. Most (98%) have diffused and heterogeneous opacity. More than (90%) concentrated in the lower third of the lungs. Median Brixia radiographic score was 8, interquartile range 5-11. The recovered group had a significantly lower median Brixia score (p<0.001) than the death group (7 vs 11 points). The rate of mild and moderate COVID-19 was 13.4%, severe 32.7%; critical 40.4%. Besides, 73.1% of cases had indication for ICU admission. 84.6% of patients need respiratory support. 30.7% of patients had to switch to invasive mechanical ventilation during follow-up. Median hospital stay was 13 days (interquartile range 10-17.75 days). The rate of intubated patients and mechanical ventilation was 31.7%. The overall mortality rate was 29.8%.
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Keywords
SARS CoV-2, COVID-19, clinical symptoms, subclinical symptoms
References
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