CLINICAL AND SUBCLINICAL CHARACTERITICS IN PATINTS WITH PERICARDIAL EFFUSION

Hoàng Văn Sỹ1,2,, Nguyễn Minh Kha1,2, Trương Phi Hùng1,2, Nguyễn Nhật Tài1, Nguyễn Hồng Phúc3, Đặng Tường Vi1
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 Cho Ray Hospital
3 Thu Duc General Hospital, Ho Chi Minh City

Main Article Content

Abstract

Background: Pericardial effusion is a common clinical condition that can occur in all ages and populations. The clinical presentation of pericardial effusion varies widely, from a clinically irrelevant, incidental finding to life – threatening cardiac tamponade. Data regarding the clinical and subclinical profiles of pericardial effusion in Vietnam are limited. Objectives: To describe clinical and subclinical in patients with pericardial effusion at Cho Ray Hospital. Patients and methods: A retrospective cross – sectional descriptive study. This study included 248 patients with confirmed diagnosis of pericardial effusion treated at Cho Ray hospital in 10 years between 2010 to 2020. Results: For 10 years, there were 285 patients with pericardial effusions, of which 248 patients who met the inclusion criteria in our study. The mean age was 52.3 ± 18, the male:female ratio was 1.61:1. Dyspnea was the most common symptom (77%), followed by chest pain (11%) and fever (4%). There were 7.7% patients with hypotension on admission, jugular venous distension was recorded in 11.3%, muffled heart sounds were 18.6%, and pulsus paradoxus was 1.6%. Circumferential distribution accounted for 95.2%, large effusion accounted for 77.4%, and 23.8% of patients showed signs of cardiac tamponade on echocardiography. Low QRS voltage and electrical alternans were 41.5% and 2%, respectively. There were 248 patients who underwent pericardiocentesis, 98% of the results were exudates. The presence of malignant cells in pericardial fluid cytology results was 12.7%. Pericardial fluid culture was positive 6/232 samples, 3 samples were positive for Staphylococcus aureus. Conclusions: The study revealed that the most common symptom of a pericardial effusion was dyspnea. Muffled heart sounds, hypotension, and jugular venous distension were rarely reported in the study. Circumferential distribution and large effusion were major. The pericardial fluid was mostly exudate, the positive culture rate was very low, and the most recognized agent was Staphylococcus aureus.

Article Details

References

1. Adler Y, Charron P, Imazio M, et al. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC)Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2015;36(42):2921-2964.
2. Albugami S, Al-Husayni F, AlMalki A, et al. Etiology of Pericardial Effusion and Outcomes Post Pericardiocentesis in the Western Region of Saudi Arabia: A Single-center Experience. Cureus. 2020; 12(1).
3. Nguyễn Thị Ngọc Thủy. Tràn dịch màng tim bệnh lý có chèn ép tim chẩn đoán và kết quả điều trị mở cửa sổ màng tim. Tạp chí Y học Thành phố Hồ Chí Minh. 2008;12(1).
4. Light RW, Macgregor MI, Luchsinger PC, et al. Pleural effusions: the diagnostic separation of transudates and exudates. Ann Intern Med. 1972;77(4):507-513.
5. Nguyễn Viết Đăng Quang. Đánh giá kết quả sớm phẫu thuật mở cửa sổ màng tim trong điều trị tràn dịch màng tim ác tính. Tạp chí Y học Thành phố Hồ Chí Minh. 2010;14(1).
6. McGinley A, Gribbin G. A delayed diagnosis of cardiac tamponade. BMJ Case Rep. 2013; 2013: bcr2012007255.
7. Văn Minh Trí. Kết quả điều trị ngoại khoa tràn dịch màng tim. Tạp chí Y học Thành phố Hồ Chí Minh. 2007;1(11).
8. Ma W, Liu J, Zeng Y, et al. Causes of moderate to large pericardial effusion requiring pericardiocentesis in 140 Han Chinese patients. Herz. 2012; 37(2):183-187.