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Date Published: 22/08/2022
Abstract Views: 321
Views PDF: 511
DOI: https://doi.org/10.51298/vmj.v517i1.3148
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Vol. 517 No. 1 (2022)
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Vũ Bảo Anh, N. ., Hà Thanh, N. ., & Quốc Chính, D. . (2022). INDUCTION TREATMENT OUTCOME OF NEWLY DIAGNOSED ESSENTIAL THROMBOCYTHEMIA PATIENTS IN NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION. Vietnam Medical Journal, 517(1). https://doi.org/10.51298/vmj.v517i1.3148

INDUCTION TREATMENT OUTCOME OF NEWLY DIAGNOSED ESSENTIAL THROMBOCYTHEMIA PATIENTS IN NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION

Nguyễn Vũ Bảo Anh1,, Nguyễn Hà Thanh1, Dương Quốc Chính2
1 Hanoi Medical University
2 National Institute of Hematology and Blood Transfusion

Main Article Content

Abstract

Objective: to study some of clinical, laboratory features and induction treatment results of newly diagnosed Essential thrombocythemia patients in National Institute of Hematology and Blood Transfusion. Patients and methods: 115 newly diagnosed and untreated patients with Essential thrombocythemia according to WHO 2008 criteria from January 2018 to December 2019 in National Institute of Hematology and Blood Transfusion. Results and conclusion: median age at diagnosis was 56, female accounted for more than male, 16.1% of patients had history or manifestation of thrombosis at the time of diagnosis, 33.9% of patients were in high-risk group according to revised IPSET thrombosis; median platelet count was 1264 G/l; JAK2 V617F, CALR and MPL mutation were 55.7%, 19.1% and 2.6%, respectively. After induction treatment, 100% of patients had at least partial response, of which, 10.4% of patients achieved a complete response.

Article Details

Keywords

Essential thrombocythemia, Myeloproliferative neoplasms, JAK2 V617F, CALR, MPL

References

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