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A RELATIONSHIP BETWEEN CAUSES AND IN-HOSPITAL OUTCOMES IN PATIENTS WITH PERICARDIAL EFFUSION
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Abstract
Background: Pericardial effusion can be caused by a variety of causes. In Viet Nam, there are few studies which survey causes and in-hospital outcomes in hospital of pericardial effusion. Objective: To survey the relationship between causes and in-hospital outcomes in patients with pericardial effusion. Materials: Patients who diagnosed pericardial effusion at Cho Ray Hospital from January 2010 to December 2020. Methods: Retrospective cross-sectional descriptive study. Results: In 10 years, we collected 285 patients with pericardial effusion, there were 248 patients who met the inclusion criteria in our study. The median age of the study population was 52,3 ± 18,0 years old, and the male gender had 153 patients (61,7%). The most frequent etiologies were malignancy (48.4%), tuberculosis (21.0%), idiopathic (10.5%) and autoimmune diseases (7.3%), whereas bacterial causes were uncommon (4.8%). In the group of malignant pericardial effusion, the most frequent malignancies originated from the lung (52.5%), invasive mediastinal tumors (13.3%) and there was many cases (20.8%) that primary origins were unknown. Only 25.8% of patients had a history of malignancy in the group of malignant pericardial effusion. The rate abnormal cytology in pericardial effusion was only 24.5% in malignant group. The pericardial fluid appearance was bloody in 64.4%, and there was statistically significant difference between the 2 groups (p=0.0001). The bad short-outcomes (death or very servere) in hospital of malignant group were similar to non-malignant group (p=0.12) but the rate of acute cardiac tomponade was higher in maligant group (30.0% vs 18.0%, p = 0.026). Conclusion: The most frequent etiology of pericardial effusion at Cho Ray Hospital was maligancy. In maligant group, the most predonimant cause was lung cancer. The short worsed outcomes in hospital of malignant group were similar to non-malignant group but the rate of acute cardiac tamponate was higher.
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Keywords
pericardial effusion, maligancy, tuberculosis
References
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