Article Sidebar
Views PDF: 160
A SURVEY OF 1,5-ANHYDROGLUCITOL LEVEL IN THE BLOOD OF PATIENTS WITH TYPE 2 DIABETES AT CHO RAY HOSPITAL
Main Article Content
Abstract
Background: 1,5-anhydroglucitol (1,5-AG) is a simple sugar found in the body. 1,5-AG test is valuable in monitoring glycemic control, supplementing HbA1c and Fructosamin. Objective: Determine the 1,5-AG level of diabetes patients and compare with the control group. Analyze the correlation between 1,5-AG and HbA1c, glycaemia. Subjects and Methods: Patients with type 2 diabetes treated at Cho Ray hospital, adults without diabetes. Descriptive cross-sectional study. Collect information about age, gender, 1,5-AG test, HbA1c, glycaemia. Non parametric test was used to compare results between groups. Results: The 1,5-AG level of diabetics (n = 133) was 2.34 (1.37-5.69) (μg/mL). The concentration of 1,5-AG in non-diabetics (n = 168) was 20.6 ± 7.09 (μg/mL). The correlation coefficient between 1,5-AG and HbA1c is r = -0.53, 1.5-AG and glycaemia is r = -0.45. Conclusions: The level of 1,5-AG in type 2 diabetic patients was lower than in non-diabetics. There was an inverse correlation between 1,5-AG and HbA1c, glycaemia.
Article Details
Keywords
Diabetes mellitus, 1,5-anhydroglucitol
References
2. Lương Quỳnh Hoa (2018), Khảo sát nồng độ 1,5-anhydroglucitol trong máu ở nhóm người trưởng thành khỏe mạnh và nhóm bệnh nhân đái tháo đường tại Bệnh viện Nội tiết Trung Ương, Luận văn cấp cơ sở, Bệnh viện Nội tiết Trung Ương, Hà Nội.
3. Lâm Vĩnh Niên Nguyễn Nguyệt Quỳnh Mai (2020), Nghiên cứu nồng độ 1,5-anhydroglucitol ở bệnh nhân đái tháo đường týp 2 và đánh giá khả năng kiểm soát đường huyết của 1,5-anhydroglucitol, Đại học Y Dược Tp. Hồ Chí Minh.
4. W. J. Kim (2012), "Serum 1,5-anhydroglucitol concentrations are a reliable index of glycemic control in type 2 diabetes with mild or moderate renal dysfunction", Diabetes Care. 35(2), 281-6.
5. Lu Chih-Chen; Lee Jenn-Kuen (2003), "1,5-anhydroglucitol levels in type 2 diabetic and non-diabetic subjects in Southern Taiwan", Endocrinologia e Metabologia. 46(6).
6. W. Nowatzke (2004), "Evaluation of an assay for serum 1,5-anhydroglucitol (GlycoMark) and determination of reference intervals on the Hitachi 917 analyzer", Clin Chim Acta. 350(1-2), 201-9.
7. T. Yamanouchi (1991), "Comparison of 1,5-anhydroglucitol, HbA1c, and fructosamine for detection of diabetes mellitus", Diabetes. 40(1), 52-7.
8. Luiza Cristina Gobor (2021), "Evaluation of 1,5-Anhydroglucitol as a Biomarker for Type 2 Diabetes Mellitus in Patients without Overt Nephropathy", Brazilian Journal of Pharmaceutical Sciences. 57.