RELATIONSHIP BETWEEN PLASMA C-REACTIVE PROTEIN CONCENTRATION WITH CAROTID ARTERIOSCLEROSIS AND PLASMA GLUCOSE CONTROL IN TYPE 2 DIABETIC MELLITUS PATIENTS
Main Article Content
Abstract
Objectives: Analysis of the relationship between plasma CRP levels and carotid atherosclerosis and blood glucose control in patients with type 2 diabetes. Subjects and methods: A cross-sectional study on 122 patients with type 2 diabetes. All patients had plasma CRP levels quantified by immunoassay turbidity, carotid Doppler ultrasound and situation of plasma glucose control according to the fasting blood glucose concentration. Results: There was a positive, moderate correlation between the CRP levels and the carotid intima-media thickness in patients with type 2 diabetes, r=0.622, p<0.001. The group of patients with carotid atherosclerosis had a 40.33 times higher risk of increasing plasma CRP levels than the non-atherosclerotic group, p<0.001. Patients with poor blood glucose control had a 2.13 times higher risk of CRP elevation compared with the group of patients with good and acceptable blood glucose control, p<0.05. Conclusion: Increased plasma CRP levels are associated with atherosclerosis and poor blood glucose control in patients with type 2 diabetes.
Article Details
Keywords
Type 2 diabetes, C-reactive protein, Atherosclerosis, Carotid Doppler ultrasound
References
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