ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ BỆNH KAWASAKI TẠI BỆNH VIỆN TRẺ EM HẢI PHÒNG

Abstract

Kawasaki disease is a syndrome of unknown cause that results in a fever and mainly affects children under 5 years of age that can cause severe damage to the coronary artery if left undetected and lack of early treatment. Objectifs: We aimed to perform this study in order to contribute to the amelioration of an early diagnosis, intime treatment and reduction of the complications of this disease.  Materials and methods: We conducted a retrospective study of 48 Kawasaki disease cases diagnosed at Hai Phong Children's Hospital from January 2016 to March 2020 and draw the following conclusion. Results: Most children with Kawasaki disease were at the age of 6 - 24 months, the rate of male/female was 1.27/1. All of patients had fever while other symptoms were found in the majority of patients. Most symptoms appeared within the first week of illness. There were 26/48 Kawasaki patients diagnosed who had been treated at the Hai Phong Children's Hospital. 92.3% of patients were treated and responded to IVIG right from the first dose, 7.7% of cases were drug resistant, requiring the 2^nd IVIG dose. There was no death case in our study. Most hematological and biochemical parameters quickly returned to normal after IVIG treatment while CRP and VSS  greatly increased and returned to normal more slowly. Conclusion: Our research showed that there is still a need for improvement in early diagnosis as still 35.5% of cases had a differrent initial diagnosis from Kawasaki, and post-treatment cardiovascular injury monitoring is essential.