ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ VI SINH CỦA BỆNH NHÂN NHIỄM KHUẨN HUYẾT DO K.PNEUMONIA TẠI BỆNH VIỆN HỮU NGHỊ

Abstract

Objectives: describe the clinical, paraclinical and microbiological characteristics of patients with sepsis caused by K.pnemonia. Subjects: 26 patients with bacteremia caused by K.pneumoniae at Huu Nghi hospital, from 1/2021 to 12/2021. Methods: Retrospective, descriptive. Results: The mean age of the patients was 85.4 ± 12.7, 65.4% of the patients were over 80%, and 92% of the patients had underlying comorbidities; 69.2% were nosocomial infections. About the way in: respiratory 65.4%, digestive, abdominal 19.2%. Clinically: From 69.2 to 92.3% of patients presents with high fever, chills, sudden onset of fever; state of consciousness disorder (57.6%), respiratory failure (57.7%), septic shock (26.9%). Mortality rate 61%, death from infection 46.2%. In terms of subclinical: inflammatory indices increased: leukocytes > 12 G/L accounted for 92.3%, over 60% of patients had CRP > 100 mg/mL or Procalcitonin > 10 ng/mL. Organ failure indicators such as: PT% < 70% accounted for 26.9%, platelets < 100 G/L accounted for 80.8%; or total Bilirubin was saved 57.7%, liver enzymes increased 71.1%, Lactate > 2 mmol/L was found in 34.6%, renal failure with urea, increased creatinine also accounted for 68.4 to 84.6%. In terms of microbiology: the level of antibiotic resistance of the K.pneumoniae strains we isolated from patients is moderate to low. Conclusion: bacteremia due to K.pnemonia mainly has access from respiratory and abdominal cavity; high rate of septic shock, multi-organ failure leading to death; moderate antibiotic sensitivity.