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SURVIVAL STUDY AND SOME FACTORS AFFECTING IN FIRST-LINE GEFITINIB TREATMENT OF ADVANCED NON-SMALL CELL LUNG CANCER WITH EGFR MUTATION
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Abstract
Objective: To study the survival and some factors influencing on the survival in advanced non- small cell lung cancer patient with EGFR mutation used Gefitinib as the primary treatment. Subject and method: 69 non- small cell lung cancer patients used Gefitinib 250 mg per day until progressive disease or unacceptable toxicity. Results: Response rate was 85,5%; Disease control rate was 94,2%; Progression free survival time 12,6 ± 1,1 months; overall survival 21,8 ± 2,5 months. The patient's overall condition and EGFR gene mutation significantly related the Progression- free survival time.
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Keywords
Non- small cell lung cancer, Gefitinib
References
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