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Date Published: 23/09/2022
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DOI: https://doi.org/10.51298/vmj.v518i1.3310
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Vol. 518 No. 1 (2022)
Section
Các bài báo
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Quang Duy, N. ., Xuân Huy, V. ., & Văn Xuân, V. . (2022). RESULTS OF TECHNICAL RADIOTHERAPY VMAT COMBINEĐAD WITH CHEMOTHERAPY WITH PACLITAXEL - CARBOPLATIN REGIMENS IN THE UPPER THIRD OF ESOPHAGEAL CANCER AT THE K HOSPITAL. Vietnam Medical Journal, 518(1). https://doi.org/10.51298/vmj.v518i1.3310

RESULTS OF TECHNICAL RADIOTHERAPY VMAT COMBINEĐAD WITH CHEMOTHERAPY WITH PACLITAXEL - CARBOPLATIN REGIMENS IN THE UPPER THIRD OF ESOPHAGEAL CANCER AT THE K HOSPITAL

Nguyễn Quang Duy1,, Vũ Xuân Huy1, Võ Văn Xuân1
1 Vietnam National Cancer Hospital

Main Article Content

Abstract

Objective: Evaluation of the results of technical radiotherapy VMAT combinedad with chemotherapy with paclitaxel - carboplatin regimens in the upper third of esophageal cancer at the K hospital. Method: An uncontrolled clinical intervention study was performed on 51 patients with esophageal cancer from August 2021 to July 2022. Results: 100% of patients responded to treatment, of which complete response was 45.1%. In terms of clinical improvement, the majority of patients had a complete response (70.6%). Undesirable effects during chemotherapy are common such as decreased hemoglobin (9.8%), leukopenia (15.4%), hepatotoxicity (13.7%), and nephrotoxicity (17.6%). Effects on other organs such as nausea (27.4%), vomiting (13.7%), stomatitis (5.9%), hair loss (39.1%). Undesirable effects during radiation therapy such as radiation esophagitis (86.3%), dermatitis (76.5%). Conclusion: This treatment regimen should be applied more commonly in the treatment of esophageal cancer due to its safety and good response.

Article Details

Keywords

Esophageal cancer, Paclitaxel-Carboplatin, chemotherapy, radiation therapy

References

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