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Date Published: 23/09/2022
Abstract Views: 977
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DOI: https://doi.org/10.51298/vmj.v518i1.3323
Issue
Vol. 518 No. 1 (2022)
Section
Các bài báo
How to Cite
Duy Hưng, N. ., Thị Việt Hà, Đặng ., Gia Tuyển, Đỗ ., & Trung Dũng, N. . (2022). EVALUATE THE CORRELATION BETWEEN ESTIMATED GLOMERULAR FILTRATION RATE USING MRDR AND CKD-EPI EQUATION WITH MEASURED GLOMERULAR FILTRATION RATE BASED ON STANDARD 12-HR CREATININE CLEARANCE. Vietnam Medical Journal, 518(1). https://doi.org/10.51298/vmj.v518i1.3323

EVALUATE THE CORRELATION BETWEEN ESTIMATED GLOMERULAR FILTRATION RATE USING MRDR AND CKD-EPI EQUATION WITH MEASURED GLOMERULAR FILTRATION RATE BASED ON STANDARD 12-HR CREATININE CLEARANCE

Nguyễn Duy Hưng1,, Đặng Thị Việt Hà2,3, Đỗ Gia Tuyển2,3, Nghiêm Trung Dũng3
1 Saint Paul Hospital
2 Hanoi Medical University
3 Urology-Nephrology and Dialysis Center, Bach Mai Hospital

Main Article Content

Abstract

Background. The aim of this study was to evaluate the correlation between estimated glomerular filtration rate (eGFR) using MDRD and CKD-EPI equation with measured glomerular filtration rate (mGFR) based on standard creatinine clearance. Subjects and methods. One prospective, cross sectional study was performed on chronic kidney disease patients with creatinine clearance made 12 hours (ClCr12h), through consensus survey correlation coefficient. Results. The study was included 218 CKD patients, the male propotion was 54,6% (n=119) and the female was 45,4% (n=99). The average age of patients was 66,64 ± 12,19 from 27 to 94 years old. The eGFR of MDRD equation performed better correlation to ClCr12h than CKD-EPI (r=0,924, r2=0,853, p<0,001 compared to r=0,916, r2=0,839, p<0,001). Degree of correlation between eGFR of MDRD and CKD-EPI equation with ClCr12h gradual decrease in stages of chronic kidney disease from stage 1 to stage 5. Conclusions. Our results suggested that there is a very strong correlation between eGFR using MDRD and CKD-EPI equation with mGFR based on standard creatinine clearance.

Article Details

Keywords

MDRD, CKD-EPI, estimated glomerular filtration rate (eGFR), creatinine clearance 12 hours (ClCr12h)

References

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