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Date Published: 23/09/2022
Abstract Views: 355
Views PDF: 196
DOI: https://doi.org/10.51298/vmj.v518i1.3354
Issue
Vol. 518 No. 1 (2022)
Section
Các bài báo
How to Cite
Kim Sơn, T. ., Hoàng Toàn, N. ., Bảo Ân, T. ., Long Thủy, M., & Trung Kiên, N. . (2022). STUDY OF THE RATES AND SOME FACTORS RELATED TO HYPERHOMOCYSTEINEMIA IN PATIENTS WITH PRIMARY HYPERTENSION. Vietnam Medical Journal, 518(1). https://doi.org/10.51298/vmj.v518i1.3354

STUDY OF THE RATES AND SOME FACTORS RELATED TO HYPERHOMOCYSTEINEMIA IN PATIENTS WITH PRIMARY HYPERTENSION

Trần Kim Sơn1,, Ngô Hoàng Toàn1, Trương Bảo Ân2, Mai Long Thủy1, Nguyễn Trung Kiên1
1 Can Tho University of Medicine and Pharmacy
2 An Giang Cardiovascular Hospital

Main Article Content

Abstract

Objectives: To determine rates of hyperhomocysteinemia, some factors related to hyperhomocysteinemia in patients with primary hypertension. Subjects and methods: A cross-sectional descriptive study was conducted on 105 patients with primary hypertension in Can Tho Medicine – Pharmacy University hospital from June 2017 to June 2018. Results: Mean homocysteinemia levels were 16.24± 4.49μmol/L. 78 patients had elevated blood homocysteine ≥15μmol/L, accounting for 74.3%. Homocysteine levels increase with age and blood pressure. Older, gender, hypertension, diabetes, and family history of early cardiovascular disease were associated with hyperhomocysteinemia. Conclusion: Hyperhomocysteinemia is a common problem in patients with primary hypertension.

Article Details

Keywords

Homocysteine, hypertension

References

1. Nguyễn Minh Hiền (2007), Homocysteine huyết thanh và mối liên quan với một số chỉ số sinh học khác trong bệnh tiền sản giật, Luận văn Thạc sỹ y học, Đại Học Y Hà Nội.
2. Ngô Thị Hiếu (2014), Nồng độ homocysteine huyết thanh ở bệnh nhân tăng huyết áp nguyên phát điều trị tại bệnh viện A tỉnh Thái Nguyên, Luận văn Thạc sỹ y học, Đại Học Y Thái Nguyên.
3. Nguyễn Thị Hương (2006), Xác định nồng độ Homocysteine trong huyết thanh bệnh nhân tăng huyết áp, Luận văn Thạc sỹ y học, Học Viện Quân Y.
4. Hội Tim mạch Việt Nam (2016), "Báo cáo của chương trình quốc gia phòng chống tăng huyết áp", Bộ Y Tế.
5. Jiang S., Pan M., Wu S. et al. (2016), "Elevation in Total Homocysteine Levels in Chinese Patients With Essential Hypertension Treated With Antihypertensive Benazepril", Clin Appl Thromb Hemost, 22 (2), pp.191-198.
6. Morris M. S., Selhub J. , Jacques P. F. (2012), "Vitamin B-12 and folate status in relation to decline in scores on the mini-mental state examination in the framingham heart study", J Am Geriatr Soc, 60 (8), pp.1457-1464.
7. Nerenberg K. A., Zarnke K. B., Leung A. A. et al. (2018), "Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children", Can J Cardiol, 34 (5), pp.506-525.
8. Tsuda K. (2018), "Associations Among Plasma Total Homocysteine Levels, Circadian Blood Pressure Variation, and Endothelial Function in Hypertension", Am J Hypertens, 31 (4), pp.e1-e2.