STUDY OF THE RATES AND SOME FACTORS RELATED TO HYPERHOMOCYSTEINEMIA IN PATIENTS WITH PRIMARY HYPERTENSION

Trần Kim Sơn1,, Ngô Hoàng Toàn1, Trương Bảo Ân2, Mai Long Thủy1, Nguyễn Trung Kiên1
1 Can Tho University of Medicine and Pharmacy
2 An Giang Cardiovascular Hospital

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Abstract

Objectives: To determine rates of hyperhomocysteinemia, some factors related to hyperhomocysteinemia in patients with primary hypertension. Subjects and methods: A cross-sectional descriptive study was conducted on 105 patients with primary hypertension in Can Tho Medicine – Pharmacy University hospital from June 2017 to June 2018. Results: Mean homocysteinemia levels were 16.24± 4.49μmol/L. 78 patients had elevated blood homocysteine ≥15μmol/L, accounting for 74.3%. Homocysteine levels increase with age and blood pressure. Older, gender, hypertension, diabetes, and family history of early cardiovascular disease were associated with hyperhomocysteinemia. Conclusion: Hyperhomocysteinemia is a common problem in patients with primary hypertension.

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