STUDY ON CLINICAL CHARACTERISTIC AND SOME RELATED FACTORS OF ACUTE PANCREATITIS AFTER ENDOSCOPIC RETROGRADE CHOLANGIO PANCREATOGRAPHY FOR REMOVAL OF COMMON BILE DUCT STONE

Nguyễn Hữu Khâm1, Dương Quang Huy2, Lê Hữu Nhượng1,, Phan Bá Danh1
1 Military Hospital 354
2 Military Hospital 103, Vietnam Military Medical University

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Abstract

Introduction: ERCP is a complicated procedure with advantages but still makes complications such as bleeding, duodenal perforation, acute pancreatitis… In these, acute pancreatitis (AP) is one early complication very common after ERCP, serious degree of AP from oedema to necrosis related to factors before and during procedure such as age, sex, Oddi Sphincter anatomy, conventional factor… Objectives: Comment some clinical, paraclinical characteristics of acute pancreatitis, and confirmation some related factors to AP after ERCP for removal of CBD stone. Subjects & Methods: A combination of prospective and retrospective on 61 patients of AP after ERCP for removal of CBD stone from 8/2020 - 7/2022 at Military Hospital 354 and Bach Mai Hospital.    Results: Mean age 63.4 ± 17.8 (18-98 y.o.); Male 54.1%, female 45.9%; Clinical symptoms: pain on right subcostal quadrant or epigastric (94.6%), fever (52.2%), jaundice (32.5%). CT and MRI: 1 stone (85.4%), almost size of stone <1cm (74%), CBD diameter 1-2cm: 82.7%. Acute cholangitis was 42.1% but almost light and mild (95%). Amylase hight with mean concentration of 529.3 U/l (maximum 5514 U/l). Acute pancreatitis on group of acute cholangitis (68.9%) higher than group without this complication (36.1%) (p<0,05). Acute pancreatitis in group with balloon stretching (65.6%) and group without technique (31%) (p<0.05). The rate of AP after ERCP of group with guidewire stent and stone ≥1 cm (67.2%) higher than stone <1cm (16.8%) (p<0.05). Conclusion: Acute pancreatitis is the most common early complication after ERCP for removal CBD stone.   

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References

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