KHẢO SÁT TÌNH HÌNH CHUYỂN ĐỔI KHÁNG SINH TỪ ĐƯỜNG TIÊM/TRUYỀN SANG ĐƯỜNG UỐNG TẠI BỆNH VIỆN THỐNG NHẤT

Abstract

Introduction: Switching from intravenous (IV) to oral (PO) antibiotics is one of the key strategies of antimicrobial stewardship programs. Conversion from IV to PO antibiotics in eligible patients can minimize IV line–related complications, reduce cost of treatment, shorten hospital stay and reduce workload for medical staff. Objectives: To evaluate the practice of switching from IV to PO antibiotics among hospitalized patients at Thong Nhat hospital. Materials and methods: A descriptive cross-sectional study was conducted on medical records of patients aged 18 years or older, prescribed at least one IV antibiotics, at Department of Infectious diseases, Thong Nhat Hospital, from January 2021 to June 2021. The appropriateness of switching from IV to OR antibiotics was assessed based on guideline for switching antibiotics of Decision 5631/QD-BYT. Results: Ninety-nine patients were included in the study, of whom 80 of the patients were eligible for IV to PO antibiotic conversion. The rate of patients switching from IV to PO antibiotics was 44.4%. The appropriate rate of switching was 43.8%. Median duration of IV therapy and length of hospital stay in converted patients was significantly shorter than the non-converted (p < 0.001).  Conclusions: The rate of from IV to PO antibiotics was not high. Apptopriate switching antibiotics helps reduce the length of hospital stay.