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EXPLORATION OF PERFORMANCE STATUS AND NEUROLOGICAL SYMPTOMS AMONG LUNG CANCER PATIENTS WITH BRAIN METASTASES AFTER 1 MONTH OF GAMMA KNIFE RADIOSURGERY AT VIETNAM NATIONAL CANCER HOSPITAL
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Abstract
Objectives: (1) To assess performance status and neurological symptoms among lung cancer patients with brain metastases after 1 month of gamma knife radiosurgery at Vietnam national cancer hospital and (2) to determine its related factors among lung cancer patients with brain metastases after 1 month of Gamma Knife radiosurgery at Vietnam National Cancer hospital. Subjects and methods: A cross sectional study was conducted among 92 lung cancer patients with brain metastases who were treated with the Gamma Knife Radiosurgery at Vietnam National Cancer hospital. Results: The Karnofsky performance scores were increased after 1 month treatment and almost patients reported at above 70 scores (92,4%, N=85). Also, all neurological symptoms were improved after 1 month of gamma knife radiosurgery. Particularly, it witnessed significant reduction of patients had suffered from headache, paralysis, sensory disorders, blurred vision, tinnitus and hearing loss after treatment, p<0.05. In addition, there were almost no significant difference in patients’ performance status and neurological symptoms among different groups in demographic characteristics, p>0.05. Conclusion: There was a positive result in patients’ performance status and their neurological symptoms after gamma knife radiosurgery. Patients with more than 2 metastases had status of tinnitus more often than the other group, p < 0.05. The tatus of tinnitus after Gamma Knife surgery needs to be evaluated and investigated in further studies to provide evidence for treatment and care activities for this group of patients.
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Keywords
Performance status, neurological symptoms, gamma knife radiosurgery, lung cancer with brain metastases
References
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