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Date Published: 09/10/2022
Abstract Views: 106
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DOI: https://doi.org/10.51298/vmj.v518i2.3459
Issue
Vol. 518 No. 2 (2022)
Section
Các bài báo
How to Cite
Hồng Hải, Đặng ., Tuấn Đạt, Đỗ ., & Duy Hưng, N. . (2022). EVALUATING SERUM ANTI-MULLERIAN HORMONE LEVELS IN GESTATIONAL TROPOBLASTIC NEOPLASIA PATIENTS TREATED WITH METHOTREXATE REGIMEN AND UTERINE PRESERVATION AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL. Vietnam Medical Journal, 518(2). https://doi.org/10.51298/vmj.v518i2.3459

EVALUATING SERUM ANTI-MULLERIAN HORMONE LEVELS IN GESTATIONAL TROPOBLASTIC NEOPLASIA PATIENTS TREATED WITH METHOTREXATE REGIMEN AND UTERINE PRESERVATION AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL

Đặng Hồng Hải1,, Đỗ Tuấn Đạt1, Nguyễn Duy Hưng1
1 Hanoi Medical University

Main Article Content

Abstract

Objectives: Evaluating serum anti-Mullerian hormone (AMH) levels in patients with gestational trophoblastic neoplasia (GTN)  treated with Methotrexate (MTX) regimen and preservation at Hanoi Obstetrics and Gynecology Hospital. Methods:This prospective study included 24 patients with GTN from August 2021 to April 2022. Results: The mean age was 26,7 ±4,93. 100% cases with FIGO scores ≤ 4 were treated MTX. The mean basal AMH level was 3,1 ±1,57ng/mL. The serum AMH levels decreased significantly after each chemotherapy cycle. The magnitude of the AMH level decline after 1st, 2nd and 3rd were 47,4±24,98; 65,9±26,75 và 72,5±27, respectively. Conclusion: The basal AMH level at diagnosis had a significant correlation with patient age. The serum AMH level decreased after each chemotherapy cycle and decline rapidly and steadily in all patients after chemotherapy.

Article Details

Keywords

gestational trophoblastic neoplasia, AMH (anti Mullerian hormone), MTX (methotrexat)

References

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