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PREPARATION OF CAPSULE CONTAINING CAESALPINIA SAPPANEXTRACT
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Abstract
Objectives: To prepare and analyze the quality of hard capsules containing Lignum Sappanfrom Caesalpinia Sappan L., Fabaceae. Materials and methods: To moc was extracted by hot extraction method to obtain the extract with 30% moisture. The hard capsule formula is selected based on the moisture, density and flow smoothness of the powdered. Results: The content of to moc extract in capsules is 160 mg. Excipients for fillers are Avicel, starch. The results showed that to moc capsules containing to moc extract had a positive reaction tested by chemical reaction. With thin layer chromatography, on the chromatogram, there are traces with the same Rf value and the same color as those on the chromatogram of reference medicinal herbs. Capsules meet the requirements of mass uniformity and disintegration of capsules. Conclusions: To Moc extract capsules were formulated. Besides, the capsule quality was investigated. As a result, it can be used to treat inflammation and pain.
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Keywords
To moc, anti-inflammatory, analgesic
References
2. Yim Dong-Gyun, Seo Jin-Kyu, Yum Hyeon-Woong, Zahid Md Ashrafuzzaman, Park Jun-Young, Parvin Rashida, Go Jonghyun, Jin Sang-Keun, Koo Ok-Kyung, Yang Han-Sul, Effects of Caesalpinia sappan L. extract on the color stability, antioxidant and antimicrobial activity in cooked pork sausages during cold storage, LWT, Vol 112, 2019.
3. Supinya Tewtrakul, Pattreeya Tungcharoen, Teeratad Sudsai, Chatchanok Karalai, Chanita Ponglimanont, Orapun Yodsaoue, Anti inflammatory and Wound Healing Effects of Caesalpinia sappan L., Phytotherapy Research, Vol 29, Issue 6, 2015.
4. Moon Hyung-In, Chung Ill-Min, Seo Su-Hyun, Kang Eun-Young, Protective effects of 3′-deoxy-4-O-methyl episappanol from Caesalpinia sappan against glutamate induced neurotoxicity in primary cultured rat cortical cells, Phytotherapy Research, Vol 24, Issue 3, 2009.
5. Jung Eui-Gil, Han Kook-Il, Hwang Seon Gu, Kwon Hyun-Jung, Patnaik Bharat Bhusan, Yong Hyun Kim, Han Man-Deuk, Brazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model, BMC Complementary Medicine and Therapies 15, 2015.
6. Jung Eui-Gil, Han Kook-Il, Kwon Hyun-Jung, Patnaik Bharat Bhusan, Kim Wan-Jong, Hur Gang Min, Nam Kung-Woo, Han Man-Deuk, Anti-inflammatory activity of sappanchalcone isolated from Caesalpinia sappan L. in a collagen-induced arthritis mouse model, Archives of Pharmacal Research 38, 2015, 973 – 983.