BỆNH LAO KHÁNG RIFAMPICIN TẠI THÁI NGUYÊN

Abstract

Objectives: to characterize the clinical situation and analyze a number of factors related to treatment outcomes for RR-TB. Methods: Descriptive study at Thai Nguyen Hospital of Tuberculosis and Lung Disease, from 2016 - 2020. Sample of all patients tested for Xpert MTB / RIF with RR-TB on standard regimen 11 months 4-6 Km Lfx Pto Cfz ZH high dose E / 5 Lfx Cfz Z E. Results: 948/4187 (22.6%) Mtb / Rif (+), obtained 83/948 (8.8%), RR-TB sourced the new TB form was 27/675 (4%); The previous antiTB treatment form was 43/215 (20%) and the extrapulmonary form was 13/58 (1.2%). There were 60 (72.3%) RR-TB on the 11-month regimen. Good outcome of treatment is 48 (80%) and poor is 12 (20%). Conclusions: RR-TB was more common in the middle-aged group, previous antiTB treatment, (AFB) smear-positive sputum, extensive lung X-ray lesions. Factors that affect poorly on treatment outcomes were: previous antiTB treatment, rales in lungs sound, smear-positive sputum and cavitary disease.