EVALUATE THE RESULTS OF ABIRATERONE ACETATE + PREDNISOLON IN METASTATIC CASTRATION-RESISTANT PROSTATE CANCER

Dương Nguyễn Khánh Linh1,, Nguyễn Thị Thái Hòa2, Lê Thị Khánh Tâm1
1 Friendship Hospital
2 Vietnam National Cancer Hospital

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Abstract

Objective: Evaluate the results of Abiraterone Acetate + Prednisolon in metastatic castration – resistant prostate cancer at Huu Nghi Hospital and K Hospital. Patients and methods: Retrospective descriptive study of 56 patients with metastatic castration – resistant prostate cancer at Huu Nghi Hospital and K Hospital from January 2015 to July 2022. Results: The mean age of patients was 74,18±7,93 years old. Common clinical symptoms at the diagnosis: bone pain (39,3%), dysuria (35,7%); urinary incontinence (30,4%); urinary retention (10,7%); hematuria (7,1%). Treatment results: the mojority of patients achieved PSA response (73,2%). Overall response rate (ORR) on images according to RECIST 1.1criteria reached 60,7%. Median progressione-free survival (PFS) was 15,8±3,8 months. Conclusion: The regimen gave good results for metastatic castration – resistant prostate cancer.

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References

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