TIẾN TRIỂN CỦA BỆNH SCHÖNLEIN – HENOCH Ở TRẺ EM

Abstract

Henoch - Schönlein purpura (HSP) - also known as IgA vasculitis, is the most common vasculitis in children. These studies describe the HSP according to its clinical morphology, as well as assessment of progress of the disease according to new diagnostic criteria are not common. Objectives: To describe the  progress of clinical morphology of HSP in children among 3 months. Methods: 84 first-time diagnosed children with HSP were hospitalized at the Viet Nam National Children's Hospital from July 2021 to June 2022. This was a cross-sectional and longitudinal study. Results: The mean age was 6.56 ± 2.61 years old. The most common clinical form of HSP  at hospital admission was the combination form without renal involvement 49%, followed by the combination with renal involvement 27%. After 3 months, 70% of patients  were recovered and 18% of patients had renal involvement, the recurrence rate was 9.52% and there was 6% changed to another clinical form. There was no  correlation between  the concentration of protein/creatinine urine  at the hospital admition and the renal involvement aftrer 3 months of treatment.  Conclusion: The overall outcome  of HSP in chidren is  good. To follow-up the concetration of protein in urine is necessary in order to identify the renal involvement.