PREPARATION OF CHLORHEXIDINE 2% ORAL ANTISEPTIC SOLUTION AND SOME CHARACTERISTICS OF THE PRODUCT IN THE LABORATORY

Phạm Thị Tuyết Nga1, Nguyễn Huyền Trang1,
1 The Odonto-Stomatology Training Institute, Hanoi Medical University

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Abstract

Chlorhexidine is an antiseptic effective against gram-negative, gram-positive bacteria and other micro organisms. Our research is done on prepared products Chlorhexidine 2% with the aim of finding out which one is the optimal formula and evaluate the physicochemical properties of the product in the laboratory. Result: Chlorhexidine 2% after preparation exists in liquid; blue color; characteristic taste; does not separate into layers and precipitates at 10-45 degrees Celsius; Chlorhexidine concentration is 1.8 %; indicators of heavy metals Arsenic (As) is 0.31ppm, lead (Pb) is 0.72ppm, mecury (Hg) is 0.19ppm. Conclusion: Prepared Chlorhexidine 2% achieves stability, safety, and organoleptic properties consistent with the requirements of a product for public use.

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References

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