RESULTS OF ORAL TONGUE CANCER TREATMENT IN YOUNG PATIENTS AT K HOSPITAL
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Abstract
Objectives: to assess oral tongue cancer treatment in young patients at K hospital. Subjects and methods: A retrospective and prospective descriptive study was conducted on 46 young patients ≤40 years old diagnosed with oral tongue cancer treated at K hospital from January 2017 to May 2022. Results: Mean age was 34.09; male/female ratio: 0.84; Early stage (I + II) accounted for 63.1%; Patients treated by surgery alone accounted for 43.5%. Patients were treated by surgery followed by radiation / adjuvant chemotherapy accounted for 41.3%. Overall 5-year survival was 82.6% with a median 51 months. The 5-year disease-free survival was 73.9% with a median 48 months. Conclusion: Tongue cancer in young people is common in women, detected at an early stage. The choice of treatment regimen depends on the stage of the disease, the patient's condition and doctor’s experience.
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Keywords
tongue cancer, young patient
References
2. Sung H. FJ, and Siegel R.L. et al.,. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians. 2021;71(3):209–249.
3. Sarkaria J.N. and Harari P.M. Oral tongue cancer in young adults less than 40 years of age: rationale for aggressive therapy. Head Neck. 1994;16(2):107–111.
4. Ngô Xuân Quý. Đánh giá kết quả điều trị ung thư lưỡi giai đoạn I, II tại bệnh viện K từ năm 2005-2010. Luận văn thạc sỹ y học, Trường Đại Học Y Hà Nội. 2010:45-65.
5. Shim S.J. CJ, and Koom W.S. et al.,. Clinical outcomes for T1-2N0-1 oral tongue cancer patients underwent surgery with and without postoperative radiotherapy. Radiat Oncol. 2010;5:43.
6. Cassidy R.J. SJM, and Jegadeesh N. et al.,. Association of Lymphovascular Space Invasion With Locoregional Failure and Survival in Patients With Node-Negative Oral Tongue Cancers. JAMA Otolaryngol Head Neck Surg. 2017;143(4):382–388.
7. Mallet Y. AN, and Le Ridant A.-M. et al.,. Head and neck cancer in young people: a series of 52 SCCs of the oral tongue in patients aged 35 years or less. Acta Otolaryngol. 2009;129(12):1503–1508.
8. Miller C. SA, and Tajudeen B. et al.,. Clinical features and outcomes in young adults with oral tongue cancer. Am J Otolaryngol. 2019;40(1):93–96.
9. Iype E.M. PM, and Mathew A. et al.,. Squamous Cell Carcinoma of the Tongue Among Young Indian Adults. Neoplasia. 2001;3(4):273–277.
10. Garavello W. SR, and Gaini R.M. et al.,. Oral tongue cancer in young patients: a matched analysis. Oral Oncol. 2007;43(9):894–897.