NHẬN XÉT ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ UNG THƯ VÚ Ở NAM GIỚI TẠI BỆNH VIỆN K

Abstract

Background: Male breast cancer occurs very rare which accounts for less than 1% of all breast cancers in general. We conduct this study to identify several clinical and subclinical features and treatment effectiveness in this population. Patients and methods: This is a retrospective study with longitudinal follow-up of 38 male patients in Viet Nam National Cancer Hospital from 2014 to 2021 who was diagnosis with breast cancer. Results: The mean age in the study group was 63.0. Time to symptom onset was 4.0 months (IQR 3.0 – 10.5) with tumor size of 21.5mm (IQR 18.0-26.7). Presence of skin invasion (T4b) accounted for 34.2%. The most common histopathology (78.9%) is invasive ductal carcinoma and the Luminal molecular subtype predominates (92.1%). The metastatic stage from primary diagnosis was 7.9%. The percentage of patients who received surgery, radiotherapy, and chemotherapy in general was 84%, 57.8%, and 78.9%, respectively. The rate of progression, recurrence and metastasis after treatment was 18.4%. Conclusions: Male breast cancer is a rare disease, although treatment is based on the guidelines of female breast cancer, the clinical features still have its own characteristics.