CLINICAL FEATURES OF SLEEP DISTURBANCES IN PROSTHETIC HEART VALVE REPLACEMENT PATIENTS

Phạm Thị Phương1,2,, Nguyễn Văn Dũng2, Nguyễn Văn Tuấn1,2
1 Hanoi Medical University
2 National Mental Health Institute, Bach Mai Hospital

Main Article Content

Abstract

Objectives: To describe the clinical features of sleep disturbances in patients with prosthetic heart valve replacement. Subjects and methods: A cross-sectional descriptive study of 97 inpatient prosthetic heart valve replacement patients at the National Heart Institute - Bach Mai Hospital from November 2021 to July 2022. Results: The average age of the study subjects was 58.8 ± 11.6; The average age for heart valve replacement was 52.3 ± 11.7 years. In our research population, 53.6% were female; the rate of a bioprosthetic heart valve and mechanical heart valve was 56.7%, and 41.2% respectively, and the remaining 2.1% of patients had both bioprosthetic and mechanical valves. 58.8% of patients with prosthetic heart valve replacement had sleep disturbances, in which difficulty maintaining sleep (94.7%) and difficulty falling asleep (84.2%) accounted for the highest proportion with the average time to fall asleep was 53.0 ± 28.1 minutes, the average number of awakenings per night was 3.0 ± 1.1 times and the average time to go back to sleep after being awake was 20.6 ± 18.0, early morning awakening accounted for 12.3% with an average early wake-up time of 13.3 ± 25.2 (minutes) and no patient had complete insomnia. The mean sleep efficiency was 66.5 ± 12.7, the mean PSQI score was 10.9 ± 3.4. Daytime manifestations in patients with sleep disturbances included fatigue (100%), decreased concentration (59.7%), nervousness, headache (29.8%), and restlessness (28.1). %), excessive drowsiness (19.3%), dizziness (19.3%), tremor (12.3%). Conclusion: Sleep disturbance is common in patients with prosthetic heart valve replacement. Difficulty falling asleep and maintaining sleep are common clinical features. Daytime manifestations are common and greatly affect the quality of life in patients with prosthetic heart valve replacement.

Article Details

References

1. Aboyans V, Johnson CO, Yadgir S, et al. Global, Regional, and National Burden of Calcific Aortic Valve and Degenerative Mitral Valve Diseases, 1990–2017. Circulation. 2020;141(21): 1670-1680.doi:10.1161/CIRCULATIONAHA. 119.043391
2. Dumesnil Jean G, Pibarot Philippe. Prosthetic Heart Valves. Circulation. 2009;119(7):1034-1048. doi:10.1161/CIRCULATIONAHA.108.778886
3. Kjersti O. Nearly one-quarter of patients say mechanical heart valve disturbs sleep. Cardiovascular Journal of Africa. 2017 Sep-Oct; 28 (5):330
4. Hedges C, Redeker NS, Ruggiero JS. Sleep Is Related to Physical Function and Emotional Well-Being After Cardiac Surgery: Nurs Res. 2004; 53(3):154-162. doi:10.1097/00006199-200405000-00002
5. Kammerlander A, Koschutnik M, Nitsche C, et al. Gender-specific differences in valvular heart disease. Wien Klin Wochenschr. 2020;132(3):61-68. doi:10.1007/s00508-019-01603-x
6. Andell P, Li X, Martinsson A, et al. Epidemiology of valvular heart disease in a Swedish nationwide hospital-based register study. Heart. 2017;103(21):1696-1703. doi:10.1136/ heartjnl-2016-310894
7. Hu XM, Huang DY, Wei WT, et al. The Assessment of Sleep Quality in Patients Following Valve Repair and Valve Replacement for Infective Endocarditis: A Retrospective Study at a Single Center. Med Sci Monit Int Med J Exp Clin Res. 2021;27:e930596-1-e930596-10. doi:10.12659/MSM.930596