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EVALUATING TREATMENT RESULTS OF COMBINATION OF TS-1 AND OXALIPLATIN IN METASTASIC GASTRIC CANCER AT VIET NAM NATIONAL CANCER HOSPITAL
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Abstract
Objective: To evaluate the efficiency of SOX chemotherapy and side effects for patients with advanced gastric cancer. Patients and methods: Description study of 32 patients with advanced gastric cancer who had received first-line chemotherapy SOX between January 2019 and February 2022. Results: After chemotherapy with SOX regimen, the rates of complete response, partial response, and stable disease were 3.1%, 53.1%, and 9.4%, respectively. The mean disease-free survival (DFS) was 7.19±4.06 months. The mean overall survival time was 12.03± 3.74 months. The most common side effect of the SOX regimen was peripheral neuropathy 68.8% (62.5% grade 1, 6.3% grade 2), followed by anemia (37.6% of which 31.3% grade 1, 6.3%) grade 2), most of the side effects were mild. Conclusion: SOX chemotherapy is an effective treatment in advanced gastric cancer.
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Keywords
advanced gastric cancer, recurrent gastric cancer, SOX chemotherapy
References
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