THE RESULTS TREATMENT FOR DRY EYE IN PRIMARY SJÖGREN SYNDROME
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Abstract
Purpose: Evaluation of the results treatment for dry eye in primary Sjögren Syndrome. Patients and method: Prospective study carried on 40 eyes of 20 patients with primary SS. The patients have OSDI≥13, TBUT≤10, SSA (+) and/or SSB (+). Collected and analized indicators were OSDI, TBUT, Shirmer I, corneal staining score, conjuntival staining score. Result: We conducted a cross sectional on 40 eyes of 20 patients with primary Sjögren’s syndrome, the results showed that: OSDI decreased significantly after 4 weeks (64.7±14.03; 49.03±14.16), TBUT decreased significantly after 4 weeks (0.7±1.16; 1.58±1.58), conjuntival staining decreased significantly after 2 weeks (10.28±3.42; 8.53±2.92), corneal staining decreased significantly after 2 weeks (12.5±2.41; 11.15±2.27), Schirmer I did not decrease significantly after 8 weeks of treatment. Conclusion: Treatment of dry eye in pSS is limited. The physical anh funtional symtoms improved slowly with the guidline combination of three drugs to treat dry eye (Restasis, Diquas, Cationorm) and systemic treatment. After 8 weeks, only 30% of the treated eyes improved in funtinal symtoms.
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Keywords
Dry eye, Sjögren’s syndrome
References
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