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Date Published: 17/10/2022
Abstract Views: 509
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DOI: https://doi.org/10.51298/vmj.v519i1.3572
Issue
Vol. 519 No. 1 (2022)
Section
Các bài báo
How to Cite
Thị Quỳnh Nga, N. ., & Thị Huyền Ninh, P. . (2022). VITAMIN D DEFICIENCY IN PRETERM INFANTS AT THE NATIONAL HOSPITAL OF PEDIATRICS. Vietnam Medical Journal, 519(1). https://doi.org/10.51298/vmj.v519i1.3572

VITAMIN D DEFICIENCY IN PRETERM INFANTS AT THE NATIONAL HOSPITAL OF PEDIATRICS

Nguyễn Thị Quỳnh Nga1, Phan Thị Huyền Ninh1,
1 Hanoi Medical University

Main Article Content

Abstract

Objectives: This study aimed to describe clinical and subclinical characteristics and evaluate some factors related to vitamin D deficiency in preterm infants. Subjects and Method: A prospective, cross-sectional descriptive study. The serum concentrations of 25-(OH)D were measured from the blood of 132 preterm infants (<32 weeks of gestation) at 3-4 weeks of post-conceptional age at the National Hospital of Pediatrics from July 1, 2021, to July 31, 2022. All patients in the present study were divided into 2 groups: vitamin D sufficiency (serum 25-(OH)D concentrations ≥50nmol/l) and vitamin D insufficiency (serum 25-(OH)Dconcentrations <50nmol/l). Results: The percentage of vitamin D insufficiency was 54.5%. There were differences in the concentrations of serum calcium, phosphorous, magnesium, and alkaline phosphatase (ALP) between the two groups. The gestational age was not significantly correlated to vitamin D insufficiency. The serum 25-(OH)D concentrations were significantly lower in the infants with abnormal maternal history, fungal infections, dysplasia, gastrointestinal problems, and hypothyroidism. Conclusion: The prevalence of vitamin D insufficiency in preterm infants is relatively high. Diseases of mothers during pregnancy, fungal infections, dysplasia, gastrointestinal problems, and hypothyroidism increase the risk of vitamin D deficiency.

Article Details

Keywords

Vitamin D deficiency, preterm infants, 25- hydroxyvitamin D

References

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