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Date Published: 17/10/2022
Abstract Views: 760
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DOI: https://doi.org/10.51298/vmj.v519i1.3574
Issue
Vol. 519 No. 1 (2022)
Section
Các bài báo
How to Cite
Minh Tuấn, V. ., Hy Triết, V. ., Thị Lệ, N. ., Quốc Tuấn, L. ., Thanh Hải, Đoàn ., & Thị Mai Dung, L. . (2022). ASSESSMENT OF THE CORRELATION OF BIOCHEMISTRY TESTS AND BIOLOGICAL PARAMETERS TO ESTIMATED GLOMERULAR FILTRATION RATE IN CHRONIC RENAL FAILURE SUBJECTS. Vietnam Medical Journal, 519(1). https://doi.org/10.51298/vmj.v519i1.3574

ASSESSMENT OF THE CORRELATION OF BIOCHEMISTRY TESTS AND BIOLOGICAL PARAMETERS TO ESTIMATED GLOMERULAR FILTRATION RATE IN CHRONIC RENAL FAILURE SUBJECTS

Võ Minh Tuấn1, Văn Hy Triết1,2,, Nguyễn Thị Lệ1,2, Lê Quốc Tuấn1,2, Đoàn Thanh Hải2, Lê Thị Mai Dung1
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 University Medical Center Ho Chi Minh City branch 2

Main Article Content

Abstract

Objectives: To investigate the correlation of biochemical tests and biological parameters with the glomerular filtration rate established by the formulas Cockcroft - Gault, MDRD, CKD - EPI 2009, 24-hour creatinine clearance on subjects with impaired renal function. chronic kidney. Methods: Cross-sectional study based on 44 Vietnamese citizens, aged 18 years or above who have chronic kidney disease. Results: Age has a low negative correlation with Cockcroft – Gault (r=-0,39); glucose has low correlation with Cockcroft – Gault (r=-0,37), MDRD (r=-0,32), CKD – EPI 2009 (r=-0,34); creatinine is highly inversely correlated with Cockcroft – Gault (r=-0,82), MDRD (r=-0,92), CKD – EPI 2009 (r=-0,90), CrCl 24h (r=0,71); urea is highly inversely correlated with Cockcroft – Gault (r=-0,63), MDRD (r=-0,73), CKD – EPI 2009 (r=-0,73), CrCl 24h (r=-0,48); Gender, BMI, blood pressure, albumin levels, protein levels and uric acid levels were not correlated with eGFR calculated by the formulas. Besides, CrCl 24h has a high positive correlation with Cockcroft – Gault (r=0,72), MDRD (0,77), CKD – EPI 2009 (0,78). The eGFR calculated by MDRD had the lowest deviation with 24h CrCl (deviation -1.44). Conclusions: There is a relationship between age, glucose, urea, and creatinine, CrCl 24h with established glomerular filtration rate; MDRD formula gives the best estimate with CrCl 24h.

Article Details

Keywords

eGFR, Cockcroft – Gault, MDRD, CKD – EPI 2009, ClCr 24h

References

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