KHẢO SÁT BIẾN CHỨNG SUY THẬN Ở BỆNH NHÂN HỘI CHỨNG THẬN HƯ NGUYÊN PHÁT NGƯỜI TRƯỞNG THÀNH

Abstract

Treatment of adult primary nephrotic syndrome is complex and often has many complications. Renal failure is one of the common complications if proper treatment is not followed and the disease response is poor. We carried out this study to investigate the rate of renal failure complications in adult primary nephrotic syndrome and analyze some factors related to renal failure complications in the study subjects. The study was carried out at the center of nephrology, urology and dialysis, Bach Mai hospital, from November 2021 to June 2022, on adult primary nephrotic syndrome patients. With a cross-sectional study design, convenient sampling, we collected and analyzed data and the results showed that 24.6% of patients had acute renal failure, 12.3% of patients had acute renal failure. chronic renal failure and 63.1% of patients without renal failure. When analyzing a number of factors related to complications of renal failure, the results showed that the rate of renal failure was lower in the group of patients with disease detection time ≥ 2 months and had been treated specifically with corticosteroids, cyclosporin. In 41 patients with pathologic results, the rate of renal failure in the group of patients with membranous glomerulonephritis was 2/2, focal glomerulosclerosis (FSGS) was 2/8 and minimal change glomerular disease. (MCD) is 5/21. Thus, specific treatment, pathologic features, and time of disease detection greatly affect renal failure complications in adult nephrotic syndrome patients.