THUỐC UỐNG DÙNG CHO TRẺ EM

Abstract

Pediatric oral formulations can be quite scientifically challenging to develop. The prerequisites for both a measurable dosage form to administer based upon bodyweight, and also taste-masking are two of the challenges for pediatric oral formulations. Oral pediatric formulations are available in some different varieties and can be either a ready-to-use formulation or require manipulation. Ready-to-use formulations include oral solution, syrup, suspension, tablets, mini-tablets, chewable tablet, orally disintegrating tablet, oral soluble films. Formulations requiring manipulation include oral powder for constitution to a solution or suspension, tablet for constitution to a suspension, effervescent tablet, mini-tablet or powder in a capsule to mix with food or drink. In this article, the various types of formulations administered orally to pediatrics are presented.  This paper also provides some recent progress in the development of pediatric formulations and delivery devices for pediatric oral administration.