TÌM HIỂU MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN KẾT QUẢ CHỌC ỐI TRONG CHẨN ĐOÁN TRƯỚC SINH TẠI BỆNH VIỆN PHỤ SẢN HẢI PHÒNG

Abstract

Prenatal screening and diagnosis are methods to detect and diagnose birth defects as well as genetic disorders. Objectives: studying some factors related to the result of amniocentesis in prenatal diagnosis at HaiPhong hospital of obstetrics and gynecology. Subjects and methods: 118 pregnant women who undergo amniocentesis. Results: There were 6 cases of abnormal fetal chromosomes (5.1%). The rate of amniocentesis for abnormal fetal chromosomal results in mother group ≥ 35 years old is 5.2 times higher than that of mother group <35 years old (p <0.05). Amniocentesis showed abnormal results in the high-risk-screening group 1.1 times higher than women with low-risk screening tests (p <0.05). Abnormal fetal morphology ultrasound had abnormal amniocentesis is 6 times higher than normal fetal ultrasound group (p <0.05). The group with abnormal history of pregnant women and families showed normal fetal chromosomal. Conclusion: The rate of amniocentesis for abnormal fetal chromosome in group mothers ≥ 35 years old is 5.2 times higher than that of group mothers <35 years old (p <0.05). The fetal abnormal ultrasound group had an abnormal amniocentesis is 6.0 times higher than the normal fetal ultrasound group (p <0.05).