ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG CỦA BỆNH VIÊM KHỚP CỘT SỐNG Ở BỆNH NHÂN NỮ GIỚI

Abstract

Objectives: To describe the clinical and subclinical characteristics of spondyloarthritis in women. Subjects and methods: A cross-sectional retrospective descriptive study was conducted on 54 female patients diagnosed with spondyloarthritis according to ASAS 2009 and ASAS 2011 criteria, treated at Rheumatology Center of Bach Mai hospital from September 2021 to July 2022. Results: The mean age of female patients was 38.52± 13.27 years old. The average time to diagnosis was 4.76± 6.24 years from symptom onset. The disease accounted for the highest rate was ankylosing spondylitis (37%), followed by psoriatic arthritis (25.9%) and reactive arthritis (1.9%) had the lowest rate. 85.2% of patients manifested with peripheral arthralgia, mainly in the lower extremities. Cervical spine pain was reported at a high rate. The mean result of Schober’s test was 3.61± 1.84 cm. Plaque psoriasis was the most common extra-articular manifestation. The rate of positive HLA-B27 was 64.8%. The mean CRP concentration was 4.51± 5.47 mg/dl. Study populations mainly had a high level of disease activity (42.6%). 62.4% axial spondyloarthritis patients had X-ray of sacroiliac joints matched to the 1984 modifed New York criteria. Conclusion: Women with spondyloarthritis have similarities and differences in disease manifestations when compared with the general population and men. Recognizing those similarities and differences helps to diagnose spondyloarthritis earlier and improve the treatment outcome.