PRELIMINARY RESULTS OF TREATMENT DYSPLASIA LESION AND EARLY GASTRIC CANCER BY ENDOSCOPIC SUBMUCOSAL DISECSSION
Main Article Content
Abstract
Objective: To assess the preliminary outcome and satefy of treatment dysplasia lesion and early gastric cancer (EGC) by endoscopic submucosal dissecsion (ESD). Subject and method: A retrospective and prospective study carried out on 35 patients with dysplasia lesion and EGC treated by ESD in 108 military central hospital between September 2018 and August 2022. Results: Rate of man and woment were 2.5:1, average age was 59,94 ± 11,78 years old. Most lesions were in antrum (80%), mainly type 0-IIac (51.4%), average size was 19.6 ± 7.5mm. The rate of en bloc resection and curative resection were 94,3% and 91,4%, respectively. The median procedure time was 65.96 min. Complications of bleeding, perforation, and surgery were 2.9%, 0%, 0%, respectively. All ulcerative lesions after ESD healed up to scarring stages within 1,5 months. After 6 months of treatment: 1 case of local recurrence was removed by ESD. Conclusion: ESD is an effective and relatively safe technique in the treatment of dysplasia lesion and early gastric cancer.
Article Details
Keywords
early gastric cancer, dysplasia, endoscopic submucosal dissecsion
References
2. Yao K., Uedo N., Kamada T., et al. (2020). Guidelines for endoscopic diagnosis of early gastric cancer. Digestive Endoscopy, 32(5): 663–698.
3. Paris Workshop Participants (2003). The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointestinal endoscopy, 58(6): 1–43.
4. Yao K. (2013). The endoscopic diagnosis of early gastric cancer. Annals of Gastroenterology : Quarterly Publication of the Hellenic Society of Gastroenterology, 26(1): 11–22.
5. Trần Đức Cảnh (2019). Nhận xét kết quả điều trị ban đầu bằng kỹ thuật ESD cho bệnh nhân ung thư dạ dày giai đoạn sớm tại bệnh viện K-Hà Nội. Hội nghị Nội soi Tiêu hóa Toàn quốc lần 4.
6. Nguyễn Thế Phương (2022). Nhận xét hiệu quả kỹ thuật cắt tách dưới niêm mạc qua nội soi điều trị tổn thương loạn sản dạ dày độ cao và ung thư dạ dày sớm. Tạp chí y học Việt Nam, 515(1), tr. 169-175.
7. Chung I., Lee J., Lee S., et al. (2009). Therapeutic outcomes in 1000 cases of endoscopic submucosal dissection for early gastric neoplasms: Korean ESD Study Group multicenter study. Gastrointestinal endoscopy, 69(7): 1228–1235.
8. Kim J.-W. and Jang J.Y. (2015). Optimal management of biopsy-proven low-grade gastric dysplasia. World Journal of Gastrointestinal Endoscopy, 7(4): 396–402.
9. Kakushima N., Yahagi N., Fujishiro M., et al. (2004). The healing process of gastric artificial ulcers after endoscopic submucosal dissection. Digestive Endoscopy, 16(4): 327–331.