PREGNANCY OUTCOME OF CASES OF CONGENITAL DIAPHRAGMATIC HERNIA IN TU DU

Bùi Thị Thu Hà1, Võ Minh Tuấn2,
1 Tu Du Hospital
2 University of Medicine and Pharmacy at Ho Chi Minh City

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Abstract

Research objectives: The mortality rate and some factors related to mortality in children with congenital diaphragmatic hernia diagnosed at Tu Du hospital in the period 2018-2022. Methods: Retrospective study of a series of 142 cases diagnosed with a diaphragmatic hernia born at Tu Du hospital from 2018 to 2021. The study results recorded the results of treatment at Tu Du, Children's I hospital, Children II hospital and Children's Hospitals in Ho Chi Minh City. Results: The mortality rate was 45/142 cases, accounting for 31.7% (CI 95%: 23.9 - 39.4). Children diagnosed with diaphragmatic hernia containing the liver had an increased risk of death 18.3 times (OR=18.3; 95% CI: 1.3 – 256.7). Children with postpartum blood pH ≤ 7.2 increased the risk of death 21.7 times compared with blood pH > 7.2 (OR=21.7; 95% CI: 2.5 - 186.2) Children with decreased SpO2 < 85% increased risk of death 32.5 times compared with SpO2 ≥ 85%. (OR=32.5; 95% CI: 1.6 – 647.1). Children with FiO2 > 40 increased the risk of death 17.7 times more than children with FiO2 ≤ 40 (OR=17.7; 95% CI: 2.3 – 136.3). Conclusion: Children diagnosed with diaphragmatic hernia before birth have a high mortality rate. Some postpartum factors such as postpartum blood pH ≤ 7.2, SpO2 <85% and children with FiO2 >40% were concluded to increase the mortality risk of diaphragmatic hernia.

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References

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