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Date Published: 28/12/2022
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DOI: https://doi.org/10.51298/vmj.v520i1.3771
Issue
Vol. 520 No. 1A (2022)
Section
Các bài báo
How to Cite
Thanh Lê, T. ., Ngọc Sơn, Đỗ ., & Quốc Chính, L. . (2022). EFFICACY OF HIGH-FLOW NASAL CANNULA OXYGEN THERAPY (HHFNC) ON PATIENTS WITH THE ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Vietnam Medical Journal, 520(1A). https://doi.org/10.51298/vmj.v520i1.3771

EFFICACY OF HIGH-FLOW NASAL CANNULA OXYGEN THERAPY (HHFNC) ON PATIENTS WITH THE ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Trần Thanh Lê1, Đỗ Ngọc Sơn2,, Lương Quốc Chính2
1 Hanoi Medical University
2 Bach Mai Hospital

Main Article Content

Abstract

Objectives: This study was conducted to evaluate the effectiveness of the heated and humidified high-flow nasal cannula (HHFNC) system on patients with the exacerbations of chronic obstructive pulmonary disease (COPD). Methods: A prospective interventional study, data was collected on all patients diagnosed with COPD exacerbation according to GOLD 2020 criteria admitted to the Center for Emegency Medicine who was on HHFNC during the period from August2021 to July 2022. Clinical indicators and blood gases were evaluated before and after HHFNC. Results: The success rate with HHFNC in patients with COPD exacerbations was 65.6% (21/32 patients). HHFNC was effective in improving clinical parameters and blood gases after 48 hours of intervention, specifically: heart rate (88.90 versus 102.72), respiratory rate (20.67 versus 27.06), SpO2 (92.24 vs. 83.66), pH (7.44 vs. 7.30), PaCO2 (46.71 vs. 61.45), PaO2 (95.34 vs 85.03) ), PaO2/FiO2 (326.19 vs 246.13), FiO2 (29.0 vs 35.31). These were statisticlly significant (p<0.05). Conclusion: HHFNC is effective in reducing the risk of intubation, improving clinical parameters and blood gases in patients with COPD exacerbations.

Article Details

Keywords

Noninvasive mechanical ventilation, HHFNC, ACOPD

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