ASSESSMENT OF CORNEAL REFRACTION POWER AND AXIS LENGTH IN HIGH MYOPIA

Nguyễn Thị Thu Hiền, Trần Phương Anh

Main Article Content

Abstract

Objective: Assessing the initial effectiveness of myopia control by Atropin 0.01% on rapidly increasing myopia children and find out some factors related to the effectiveness of myopia control with Atropin 0.01%. Research methods: clinical trial studies without control group, the study was conducted on 54 eyes with a myopia progress rate of over 1,00 D/year in the refraction department of Vietnam National Eye Hospital. Results: All cases after using Atropin 0.01% were no glare, redness, and difficulty in near vision. Myopia progress rate: after 6 months of using Atropin 0.01%, the average rate of increase in myopia power was 0.62 ± 0.69 D/year, after 12 months of using the drug, the average rate of increase in myopia power was 0.47 ± 0.43 D/ year. Axis length: after 6 months it was longer 0.18 ± 0.11mm (p<0.001), compared to 6 months, after 12 months it was longer 0.15 ± 0.82mm (p>0.05). The accommondation amplitude decreased after 2 weeks of using Atropin 0.01%, recovered after 6 months and 12 months of dropping the drug. The pupil size dilated slightly after 2 weeks of using Atropin 0.01%, recovered after 6 months and 12 months of dropping the drug. Conclusion: After using Atropin 0.01% in myopia children, the rate of myopia progress decreased and near vision was not affectted.

Article Details

References

1. Chia A, Chua WH, Cheung YB, Wong WL, Lingham A, Fong A, et al. Atropine for the treatment of childhood myopia: safety and efficacy of 0.5%, 0.1%, and 0.01% doses (Atropine for the Treatment of Myopia 2). Ophthalmology. 2012 Feb;119(2):347-54. PubMed PMID: 21963266.
2. Chia A, Chua WH, Wen L, Fong A, Goon YY, Tan D. Atropine for the treatment of childhood myopia: changes after stopping Atropine 0.01%, 0.1% and 0.5%. American journal of ophthalmology. 2014 Feb;157(2):451-7 e1. PubMed PMID: 24315293.
3. Chua WH, Balakrishnan V, Chan YH, Tong L, Ling Y, Quah BL, et al. Atropine for the treatment of childhood myopia. Ophthalmology. 2006 Dec;113(12):2285-91. PubMed PMID: 16996612.
4. Hoàng Quang Bình. Thực trạng tật khúc xạ của học sinh một số trường tiểu học và trung học cơ sở Cần Thơ năm học 2013-2014. Tạp chí Y học Việt Nam. 2016;442(1):187-90
5. Polling JR, Kok RG, Tideman JW, Meskat B, Klaver CC. Effectiveness study of Atropine for progressive myopia in Europeans. Eye. 2016 Jul;30(7):998-1004. PubMed PMID: 27101751. Pubmed Central PMCID: 4941076.
6. Shih YF, Chen CH, Chou AC, Ho TC, Lin LL, Hung PT. Effects of different concentrations of Atropine on controlling myopia in myopic children. Journal of ocular pharmacology and therapeutics: the official journal of the Association for Ocular Pharmacology and Therapeutics. 1999 Feb;15(1):85-90. PubMed PMID: 10048351
7. Tran HDM, Tran YH, Tran TD, Jong M, Coroneo M, Sankaridurg P. A Review of Myopia Control with Atropine. Journal of ocular pharmacology and therapeutics: the official journal of the Association for Ocular Pharmacology and Therapeutics. 2018 Jun;34(5):374-9. PubMed PMID: 29715053.
8. Yam JC, Jiang Y, Tang SM, Law AKP, Chan JJ, Wong E, et al. Low-Concentration Atropine for Myopia Progression (LAMP) Study: A Randomized, Double-Blinded, Placebo-Controlled Trial of 0.05%, 0.025%, and 0.01% Atropine Eye Drops in Myopia Control. Ophthalmology. 2019 Jan;126(1):113-24. PubMed PMID: 30514630.