KHẢO SÁT TỶ LỆ VI NẤM TRÊN BỆNH NHÂN THỞ MÁY TẠI KHOA HỒI SỨC TÍCH CỰC BỆNH VIỆN NGUYỄN TRÃI

Abstract

Background: Mechanical ventilation is one of the indispensable resuscitation methods in the Intensive Care Unit. Mechanical ventilation pneumonia is a common nosocomial infection, includes bacterial and fungal pathogens. Among the fungal agents, Candida spp and Aspergilus spp account for the highest percentage, fungal infections in elderly patients (with weakened immune systems) need to be taken care of in order to minimize the mortality of patients. Objectives: To determine the rate of vulvovaginal fungi in mechanical ventilation patients in the Intensive Care Unit, Nguyen Trai Hospital and related factors. Subjects and Methods: Applying  a  cross sectional  study  on  102 ventilator patients at the Intensive Care Unit,  Nguyen Trai Hospital  from March 2022 to September 2022. Results: 102 ventilators patients at the Intensive Care Unit of Nguyen Trai Hospital participated in the study, including 53 men and 49 women. There was a statistically significant relationship between the rate of fungal infections and the number of days of mechanical ventilation (p < 0.05). The percentage of fungi in microscopic examination was 28.4%, in which Candida spp was 82.8%, Aspergilus spp was 17.2%. The majority of Candida spp isolated were Candida albicans 44.8%, the rest were candida non-albicans including: Candida glarata (20.7), Candida tropicalis (13.8)… Factors associated with fungal infections in mechanically ventilated patients were gender (OR=2.69), diabetic patients (OR=1.04), fever symptoms (OR=2.51). Conclusion: The rate of fungi in mechanical ventilation patients was 28.4%. Common pathogenic fungi were Candida spp (82.8%), in which Candida albicans accounts for the highest rate 44.8%, Aspergilus spp (17.2%). There was a relationship between fungal infections in mechanically ventilated patients with the number of days on mechanical ventilation, a high rate in male, diabetic patients, and fever.