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Date Published: 10/02/2023
Abstract Views: 712
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DOI: https://doi.org/10.51298/vmj.v520i1B.3913
Issue
Vol. 520 No. 1B (2022)
Section
Các bài báo
How to Cite
Võ , L. M. P., Nguyễn , H. K., & Mai , H. N. (2023). SURVEYING THE OBSERVATION MODEL IN MICE (SWISS ALBINO) BY HIGH LIPID DIET WITH VARYING RATIOS OF FAT CONTENT. Vietnam Medical Journal, 520(1B). https://doi.org/10.51298/vmj.v520i1B.3913

SURVEYING THE OBSERVATION MODEL IN MICE (SWISS ALBINO) BY HIGH LIPID DIET WITH VARYING RATIOS OF FAT CONTENT

Lê Mai Phương Võ 1, Hào Khang Nguyễn 2, Huỳnh Như Mai 2
1 Can Tho University of Medicine and Pharmacy
2 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Background: Animal models of obesity have been used for a long time in the world to imitate diseases in humans but has not standardized in Viet Nam. Objectives: The study aims to found a high-fat diet with a defined fat content ratio that can create a achieving obese mouse model. Methods: In vivo experimental study on five-week-old mice was fed a regular diet (control batch) and a high-fat diet with different fat contents (20%, 40% and 60%) (trial batch) for 08 weeks. The trial mice were considered obese when their body weight was 40% higher than the control mice. Results: Diet containing 40% and 60% fat content produced a achieving obese mouse model. Conclusion: The research team has built a high-fat diet with a different fat content ratio that can create an experimental obesity mouse model.

Article Details

Keywords

obesity model, mouse model, fat content.

References

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