ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ NẤM MÓNG TAY BẰNG LASER ND: YAG 1064 NM XUNG DÀI KẾT HỢP UỐNG ITRACONAZOLE

Abstract

Objectives: To evaluate the efficacy long pulse Nd:YAG 1064 nm laser combined with oral itraconazole in the treatment of onychomycosis. Methods: Descriptive cross-sectional study, longitudinal follow-up, prospective. Results: There were 31 selected patients, most of the study subjects were female (71.0%).The mean age was 41.96 ± 14.37 years old. The mean duration of disease was 31,52 ± 31,26 months. The mean OSI index gradually decreased over time of treatment. From 22,87 ± 7,89 points before treatment, down to 18,71 ± 6,01 points after 4 weeks of treatment and down to 13,55±7,06 points after 8 weeks of treatment. After 4 weeks, the average OSI score decreased by 5,05 ± 3,58 points compared to before treatment and after 8 weeks, the mean OSI score decreased by 10,4 ± 5,98 points compared to before treatment. After 04 weeks of treatment, test results showed that 95,2% of patients had not been cured, 4,8% of patients tested for suspicious results. After 8 weeks, 20% of patients with test results were cured, 80% of patients with test results were still not cured. During the course of the study, there were no cases of side effects from itraconazole. There were only 02 cases of mild burns after laser. Conclusion: Long-pulse Nd:YAG 1064 nm laser combined with oral itraconazole are effective clinically and on laboratory tests after 8 weeks in the treatment of oncychomycosis. During the course of the study, there were no cases of side effects from itraconazole. There were only 02 cases of mild burns after laser.