U ĐỆM DÂY SINH DỤC BUỒNG TRỨNG: GIÁ TRỊ HẠN CHẾ CỦA CHỈ SỐ NGUY CƠ ÁC TÍNH

Abstract

Purpose: We aimed to assess the clinical, paraclinical features ovarian sex cord-stromal tumors and analyse the eficiency of risk of malignancy index (RMI) scoring system to detecting malignancy among these tumors. Materials and Methods: Medical records of 68 casesdiagnosed ovarian sex cord-stromal tumorsfrom 2016 through 2020 in Vietnam National Cancer Hospital were reviewed retrospectively. Results: Patients with mean age of 51.6 ± 16.1 (range:15-81 years old)were reviewed, 61.8% of cases were postmenopausal. The most common symptom was abdominal pain (70.6%).On ultrasonography, the majority of masses were the mixed betweensolid and cyst. Analyzing RMI score, there were 32 high-risk cases, 36 low-risk cases, RMI mean was 542.9 ± 917.2 (range: 0 – 4271). Sensitivity, specificity, positive predictive value, and negative predictive value of the RMI scoring for identification of malignant lesions preoperatively were found as 48%, 53.7%, 28.3%, and 40%, respectively. Conclusion: Ovarian sex cord-stromal tumors are uncommon, oftenoccur in postmenopausal patients. RMI scoring is not effective for detecting malignant tumors preoperatively. Further studies with higher number of cases are needed to state clearly the role of RMI scores.