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Issue: Vol. 521 No. 1 (2022)
Section: Các bài báo
DOI: 10.51298/vmj.v521i1.3947
Date Published: 15/12/2022
Views 283
Downloads 197
How to Cite
Trần, N. T., Nguyễn, P. H., & Dương, H. T. (2023). C-MET EXPRESSION IN GASTRIC ADENOCARCINOMA. Vietnam Medical Journal, 521(1). https://doi.org/10.51298/vmj.v521i1.3947

C-MET EXPRESSION IN GASTRIC ADENOCARCINOMA

Ngọc Thụy Trần1, , Phú Hùng Nguyễn2, Hồng Thái Dương1
1 Thai Nguyen University Of Medicine And Pharmacy
2 Thai Nguyen University of Sciences

Main Article Content

Abstract

Objectives: To evaluate the level of C-met expression and its relationship with the endoscopic and histopathological features of patients with gastric antral adenocarcinoma. Subjects and methods: The study was performed on 150 cases of gastric adenocarcinoma operated at Hanoi K Hospital from January 2018 to december 2019 by cross-sectional descriptive method. Results: C-met expression was found in 51.3% of gastric adenocarcinomas. Expression of C-met in infiltrates, polyps, ulcers and polypoid was 41.7%, 50%, 51.3% and 53.7% (p > 0.05). According to Lauren's histological classification, 56,9% of intestinal type tumors  had C-met expression compared to 26.5% off diffused types and 85,7% of mixed types, respectively (p < 0.01). Accorrding to Expression of C-met was different in mixed 85.7% papillary 66.7%, mucinous 66.7%, tubular 54.5% and signet ring cell 26.5% types (p < 0.05). Expression of C-met in different grades: 48.3% of well-differentiated, 62.5%  of moderately differentiated and 43.1% of poorly differentiated tumors (p > 0.05).

Keywords

C-met, gastric adenocacinoma, intestinal type, diffuse type

Article Details

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