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Date Published: 13/02/2023
Abstract Views: 281
Views PDF: 143
DOI: https://doi.org/10.51298/vmj.v521i1.3975
Issue
Vol. 521 No. 1 (2022)
Section
Các bài báo
How to Cite
Trần, T. T. T., & Lê, T. T. H. (2023). THE VALUE OF FIBROSIS INDEX FIB-4 IN ASSESSMENT OF LIVER FIBROSIS STAGE IN IN PATIENTS WITH ALCOHOLIC LIVER DISEASE. Vietnam Medical Journal, 521(1). https://doi.org/10.51298/vmj.v521i1.3975

THE VALUE OF FIBROSIS INDEX FIB-4 IN ASSESSMENT OF LIVER FIBROSIS STAGE IN IN PATIENTS WITH ALCOHOLIC LIVER DISEASE

Thị Thanh Thư Trần1,, Thị Thu Hiền Lê1
1 Thai Nguyen University Of Medicine And Pharmacy

Main Article Content

Abstract

Objectives: To evaluate the value of the FIB-4 in assessing the liver fibrosis stage in patients with alcoholic liver disease. Subjects and Methods: A cross-sectional descriptive study on 49 patients with alcoholic liver disease diagnosed by elastography of liver tissue. Results: Mean age was 54.8 ± 7.4 years, 100% male. The FIB-4 tends to increase gradually according to the severity of liver fibrosis: F1 (1.0 ± 0.6), F2 (3.0 ± 1.6) and to F4 (5.2 ± 2.4). To diagnose cirrhosis: the threshold value of FIB-4 is 2.6; the area under the ROC curve was 0.823 (p < 0.05; 95% CI: 0.679 – 0.967); Sensitivity and specificity were 89.5% and 73%, respectively. The value of FIB-4 in the assessment of liver fibrosis, the area under the ROC curve was 0.77 (p < 0.05, 95% CI: 0.513–1). Conclusion: FIB-4 is valuable in assessing the liver fibrosis stage in patients with alcoholic liver disease.

Article Details

Keywords

FIB-4, Liver fibrosis, Alcoholic liver disease

References

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