KẾT QUẢ ĐIỀU TRỊ VIÊM LOÉT GIÁC MẠC DO MICROSPORIDIA BẰNG PHẪU THUẬT GHÉP GIÁC MẠC XUYÊN

Abstract

Purpose: To evaluate outcomes of  therapeutic penetrating keratoplasty (PKP) for treating Microsporidial stromal keratitis at Viet Nam National Eye Hospital. Methods: A retrospective, cross-sectional descriptive study on 63 eyes of 62 patients who underwent therapeutic corneal transplantation for treating Microsporidial keratitis at the National Eye Hospital from January 2018 to December 2020. The outcome of PKP were measured in term of: eradication of disease, anatomical success, visual acuity, and graft clarity, surgical complications. Results: In all, 63 eyes of 62 patients were enrolled in the study, 74,6% of patients were female. Average age was 60.8±10.1 years. Average follow-up period was 33.5 ±10.1 months. Overall anatomical success rate was 98.4%, cure rate of infection was 84.1%, graft clarity was 36.7%. Corneal graft infection rate was 15.9%. The common postoperative complications included delayed epithelization of corneal graft, corneal graft rejection, secondary glaucoma. Two eyes need to do re-graft in which one eye had primary graft failure and one eye had unreversed graft rejection. On the last follow-up, 22 grafts (37,1%) remained clear with avearage follow-up of 33.5 months. Last follow-up visual acuity was improved compared with preoperative visual acuity. Conclusions: Penetrating keratoplasty is appeared to be an appropriate treatment for Microsporidial keratitis.